Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Infectious Diseases

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%

Mortality at 12 months · people living with HIV

It is very uncertain whether rapid antiretroviral therapy (ART) changes mortality at 12 months compared with standard care (very low certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 0.72 [0.51, 1.01]
7 studies · 5451 participants
Very low

HIV virological suppression at 6 months (viral load < 400 copies/mL) · people living with HIV

Rapid antiretroviral therapy (ART) probably leads to higher virological suppression at 12 months compared with standard care (moderate certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 1.18 [1.1, 1.27]
4 studies · 2719 participants
Moderate

Retention in care at 12 months · people living with HIV

Rapid antiretroviral therapy (ART) may leads to higher retention in care at 12 months compared with standard care (low certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 1.22 [1.11, 1.35]
6 studies · 5001 participants
Low

Uptake of ART at 90 days · people living with HIV

Rapid antiretroviral therapy (ART) may leads to higher uptake of ART at 90 days compared with standard care (low certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 1.31 [1.18, 1.45]
4 studies · 11404 participants
Low

Uptake of ART at 12 months · people living with HIV

Rapid antiretroviral therapy (ART) probably leads to higher uptake of ART at 12 months compared with standard care (moderate certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 1.09 [1.06, 1.12]
4 studies · 3713 participants
Moderate

Treatment modification · people living with HIV

It is very uncertain whether rapid antiretroviral therapy (ART) changes treatment modification compared with standard care (very low certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 7.89 [0.76, 81.74]
2 studies · 977 participants
Very low