Findings

What do systematic reviews say?

9 questions · 9 findings · 2 reviews · Breast Cancer

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No studies found 0 · 0%GRADE not reported 5 · 55.6%Very low 0 · 0%Low 1 · 11.1%Moderate 1 · 11.1%High 2 · 22.2%

Radiotherapy vs full axillary surgery

All‐cause mortality · women with operable primary breast cancer

Radiotherapy alone showed no clear difference in all‐cause mortality compared with full axillary surgery (high certainty).

1 finding from 1 review

Axillary treatment for operable primary breast cancer 2017 · Cochrane Headline outcomes only
HR 1.1 [1, 1.21]
4 studies · 2469 participants
High

Radiotherapy vs full axillary surgery

Local recurrence · women with operable primary breast cancer

Radiotherapy alone leads to lower local recurrence compared with full axillary surgery (high certainty).

1 finding from 1 review

Axillary treatment for operable primary breast cancer 2017 · Cochrane Headline outcomes only
HR 0.8 [0.64, 0.99]
4 studies · 22256 participants
High

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Locoregional recurrence · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) may leads to lower local and regional recurrence (LRR) compared with no PMRT (low certainty).

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
HR 0.2 [0.13, 0.33]
1 study · 552 participants
Low

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Overall survival (OS) · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) probably leads to lower overall survival (OS) compared with no PMRT (moderate certainty).

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
HR 0.76 [0.6, 0.97]
1 study · 552 participants
Moderate

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Disease-free survival · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Time to progression · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Short‐term adverse events · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Long‐term adverse events · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

QoL · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported