Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 25 findings · 4 reviews

No studies found 12 · 48%GRADE not reported 5 · 20%Very low 3 · 12%Low 3 · 12%Moderate 2 · 8%High 0 · 0%

Propranolol vs placebo

Treatment efficacy CAPS, CIDI · adult participants (18 years and older) who have been exposed to any traumatic events, but who did not meet the diagnostic criteria for…

Propranolol showed no clear difference in treatment efficacy CAPS, CIDI compared with placebo (low certainty).

1 finding from 1 review

Oral propranolol vs placebo

Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol probably leads to higher clearance, as assessed by a clinician at any compared with placebo (moderate certainty).

1 finding from 1 review

Oral propranolol vs topical timolol

Adverse events experienced at short or long term ‐ general adverse events 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin

It is very uncertain whether oral propranolol changes adverse events experienced at short or long term ‐ general adverse… compared with topical timolol (very low certainty).

1 finding from 1 review

Oral propranolol vs topical timolol

Other measures of resolution, as assessed by a clinician, at any · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol showed no clear difference in other measures of resolution, as assessed by a clinician, at any compared with topical timolol (low certainty).

1 finding from 1 review

Oral propranolol vs placebo

A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Oral propranolol vs placebo

Adverse events experienced at short or long term ‐ Serious adverse events 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol showed no clear difference in adverse events experienced at short or long term ‐ Serious adverse… compared with placebo (low certainty).

1 finding from 1 review

Oral propranolol vs placebo

Other measures of resolution, as assessed by a clinician, at any · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol showed no clear difference in other measures of resolution, as assessed by a clinician, at any compared with placebo (moderate certainty).

1 finding from 1 review