Findings

What do systematic reviews say?

4 questions · 4 findings · 4 reviews

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No studies found 0 · 0%GRADE not reported 1 · 25%Very low 2 · 50%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Probiotics vs placebo

Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Probiotics for management of functional abdominal pain disorders in children 2023 · Cochrane Headline outcomes only
RR 1 [0.07, 15.12]
8 studies · 544 participants
Very low

Probiotics vs placebo

Withdrawals due to adverse events · children with chronic constipation without a physical explanation

Probiotic showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Probiotics for treatment of chronic constipation in children 2022 · Cochrane Headline outcomes only
RR 0.64 [0.21, 1.95]
5 studies · 357 participants
Low

Probiotics vs placebo

Withdrawals due to adverse events · children with Hirschsprung's disease (HD)

1 finding from 1 review

Probiotics for the prevention of Hirschsprung‐associated enterocolitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Antibiotics plus probiotics vs placebo or no intervention

Withdrawals due to adverse events · people with active UC

It is very uncertain whether antibiotics plus probiotics changes withdrawals due to adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 1 [0.07, 15.08]
2 studies · 98 participants
Very low