Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Adverse events · children up to age 18 years

Probiotic showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Probiotics for preventing acute otitis media in children 2019 · Cochrane Headline outcomes only
OR 1.54 [0.6, 3.94]
4 studies · 395 participants
Low

Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes adverse events (any) compared with placebo (very low certainty).

1 finding from 1 review

Probiotics for management of functional abdominal pain disorders in children 2023 · Cochrane Headline outcomes only
RR 1 [0.07, 15.12]
7 studies · 489 participants
Very low

Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders

1 finding from 1 review

Probiotics for management of functional abdominal pain disorders in children 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 685 participants
Very low

Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Probiotics for management of functional abdominal pain disorders in children 2023 · Cochrane Headline outcomes only
RR 1 [0.07, 15.12]
8 studies · 544 participants
Very low