Findings

What do systematic reviews say?

27 questions · 28 findings · 2 reviews

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No studies found 3 · 10.7%GRADE not reported 2 · 7.1%Very low 0 · 0%Low 8 · 28.6%Moderate 9 · 32.1%High 6 · 21.4%

Pregabalin 300 mg vs placebo

Vomiting · women having medical abortion before 14 weeks' gestation

Summary of findings table ‐ Pregabalin 300 mg showed no clear difference in gastrointestinal side effects (vomiting) compared with placebo (low certainty).

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
OR 0.76 [0.35, 1.63]
1 study · 107 participants
Low

Pregabalin 300 mg vs placebo

Diarrhoea · women having medical abortion before 14 weeks' gestation

Summary of findings table ‐ Pregabalin 300 mg showed no clear difference in gastrointestinal side effects (diarrhoea) compared with placebo (low certainty).

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
OR 0.82 [0.38, 1.76]
1 study · 107 participants
Low

Pregabalin 300 mg vs placebo

Complete abortion rate ‐ not reported · women having medical abortion before 14 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pregabalin 300 mg vs placebo

Induction to expulsion interval ‐ not reported · women having medical abortion before 14 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pregabalin 300 mg vs placebo

Unscheduled contact with care ‐ not reported · women having medical abortion before 14 weeks' gestation

The review found no eligible studies for this question.

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pregabalin 300 mg vs placebo

Patient satisfaction with analgesia ‐ not reported · women having medical abortion before 14 weeks' gestation

Summary of findings table ‐ Pregabalin 300 mg showed no clear difference in patient satisfaction with analgesia compared with placebo (low certainty).

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
OR 0.97 [0.42, 2.21]
1 study · 104 participants
Low

Pregabalin 300 mg vs placebo

Patient satisfaction with abortion care overall ‐ not reported · women having medical abortion before 14 weeks' gestation

Summary of findings table ‐ Pregabalin 300 mg showed no clear difference in patient satisfaction with abortion care overall compared with placebo (low certainty).

1 finding from 1 review

Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
OR 1.84 [0.8, 4.22]
1 study · 105 participants
Low