Findings

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9 questions · 9 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 22.2%Low 5 · 55.6%Moderate 1 · 11.1%High 1 · 11.1%

Pre‐hospital vs in‐hospital thrombolysis

All‐cause hospital mortality · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in all‐cause hospital mortality compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0.73 [0.37, 1.41]
3 studies · 538 participants
Low

Pre‐hospital vs in‐hospital thrombolysis

Time to thrombolytic treatment [minutes] · participants with ST‐elevation myocardial infarction

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 438 participants
High

Pre‐hospital vs in‐hospital thrombolysis

Acute myocardial infarction functional outcomes ‐ ejection fraction [percentage] · participants with ST‐elevation myocardial infarction

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 416 participants
Low

Pre‐hospital vs in‐hospital thrombolysis

Adverse effects ‐ ventricular Fribrillation · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ ventricular Fribrillation compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 2.73 [0.68, 10.86]
2 studies · 178 participants
Low

Pre‐hospital vs in‐hospital thrombolysis

Adverse effects ‐ bleeding complications · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ bleeding complications compared with in‐hospital thrombolysis (moderate certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0.88 [0.41, 1.92]
2 studies · 438 participants
Moderate

Pre‐hospital vs in‐hospital thrombolysis

Allergic adverse events · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ allergic reaction compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 0 [0.19, 77.03]
1 study · 100 participants
Low

Pre‐hospital vs in‐hospital thrombolysis

Adverse effects ‐ Stroke · participants with ST‐elevation myocardial infarction

Pre‐hospital showed no clear difference in adverse effects ‐ Stroke compared with in‐hospital thrombolysis (low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
RR 2.11 [0.39, 11.4]
1 study · 360 participants
Low

Pre‐hospital cooling vs in‐hospital cooling

Survival to hospital discharge with good neurological function · patients with out‐of‐hospital cardiac arrest

1 finding from 1 review

Pre‐hospital versus in‐hospital initiation of cooling for survival and neuroprotection after out‐of‐hospital cardiac… 2016 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2369 participants
Very low

Pre‐hospital cooling vs in‐hospital cooling

Adverse events ‐ re‐arrest after randomization · patients with out‐of‐hospital cardiac arrest

It is very uncertain whether pre‐hospital cooling changes adverse events ‐ re‐arrest after randomization compared with in‐hospital cooling (very low certainty).

1 finding from 1 review

Pre‐hospital versus in‐hospital initiation of cooling for survival and neuroprotection after out‐of‐hospital cardiac… 2016 · Cochrane Headline outcomes only
RR 1.23 [1.02, 1.48]
4 studies · 1713 participants
Very low