Cochrane · systematic review · CD010570

Pre‐hospital versus in‐hospital initiation of cooling for survival and neuroprotection after out‐of‐hospital cardiac arrest

Arrich, J, Holzer, M, Havel, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Pre‐hospital cooling compared to in‐hospital cooling for survival, neuroprotection, and adverse events after out‐of‐hospital cardiac arrest

Population: out‐of‐hospital cardiac arrest
2 questions
OutcomeEffectEvidenceStatus / GRADE
Survival and good neurological outcome
Pre‐hospital cooling vs in‐hospital cooling
no estimate extracted7 studies · 2369 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events ‐ re‐arrest after randomization
Pre‐hospital cooling vs in‐hospital cooling
RR 1.23 [1.02, 1.48]4 studies · 1713 participantsVery low
Downgraded: risk of bias, imprecision, indirectness