Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Anaesthesia

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 33.3%High 2 · 66.7%

Injection site pain · Patients requiring local anaesthesia

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 685 participants
Moderate

Personal preference · Patients requiring local anaesthesia

Plain lidocaine leads to higher preference compared with buffered lidocaine (high certainty).

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
OR 3.01 [1.19, 4.15]
8 studies · 346 participants
High

Adverse events · Patients requiring local anaesthesia

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 182 participants
High