Findings

What do systematic reviews say?

5 questions · 11 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 63.6%Low 4 · 36.4%Moderate 0 · 0%High 0 · 0%

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).

4 findings from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 1.06 [0.63, 1.8]
66 participants
Very low
Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 2.01 [1.69, 2.38]
361 participants
Low
Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 0.95 [0.65, 1.37]
72 participants
Very low

Show 1 more finding

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 1 [0.95, 1.05]
1 study · 74 participants
Low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 1.03 [0.86, 1.24]
69 participants
Very low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 1.04 [0.9, 1.2]
35 participants
Very low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: methadone versus methadone plus gabapentin · management of opium withdrawal

Pharmacological detoxification treatment showed no clear difference in completion of treatment: methadone versus methadone plus gabapentin compared with other pharmacological detoxification treatment (low certainty).

1 finding from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 1.17 [0.96, 1.43]
1 study · 40 participants
Low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Withdrawal symptoms · management of opium withdrawal

4 findings from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
no estimate extracted
72 participants
Very low
Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low
Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
no estimate extracted
60 participants
Very low

Show 1 more finding

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
no estimate extracted
34 participants
Very low