Findings

What do systematic reviews say?

49 questions · 51 findings · 4 reviews

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No studies found 15 · 29.4%GRADE not reported 3 · 5.9%Very low 6 · 11.8%Low 15 · 29.4%Moderate 11 · 21.6%High 1 · 2%

Phacoemulsification vs phacoemulsification plus viscogonioplasty

Mean change in IOP measured in mmHg 12 months postintervention · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
91 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with IOP control (higher number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

Phacoemulsification may leads to higher proportion of participants with IOP control (higher number of events… compared with laser peripheral iridotomy (low certainty).

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
RR 1.66 [1.28, 2.15]
2 studies · 97 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
RR 0.07 [0.01, 0.51]
2 studies · 99 participants
Very low

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with 1 or more recurrent APAC episodes in the same eye (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants with 1 or more recurrent APAC episodes in… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.3]
1 study · 37 participants
Very low

Phacoemulsification vs laser peripheral iridotomy

Mean number of antiglaucoma medications at 1‐year · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Mean IOP ( · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Mean change in angle findings, measured by any method · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 94 participants
Very low

Phacoemulsification vs laser peripheral iridotomy

Adverse effects · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

1 finding from 1 review

Lens extraction versus laser peripheral iridotomy for acute primary angle closure 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 99 participants
Low

Phacoemulsification vs laser peripheral iridotomy

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · participants with primary angle‐closure glaucoma

Phacoemulsification probably leads to lower progression of visual field loss (worsening of one or more stages,… compared with laser peripheral iridotomy (moderate certainty).

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
OR 0.35 [0.13, 0.91]
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Mean change in IOP measured in mmHg 12 months postintervention · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Mean number of antiglaucoma medications at 1‐year · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Gonioscopic findings · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Visual acuity · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Phacoemulsification vs laser peripheral iridotomy

Adverse effects · participants with primary angle‐closure glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Phacoemulsification vs laser peripheral iridotomy

Quality of life measures(measured on the EQ‐5D; higher = better) (at 12 months) · participants with primary angle‐closure glaucoma

1 finding from 1 review

Lens extraction for chronic angle‐closure glaucoma 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

IStent in combination with phacoemulsification vs phacoemulsification alone

Proportion of participants who were drop‐free · open‐angle glaucoma

It is very uncertain whether IStent in combination with phacoemulsification changes proportion of participants who were drop‐free compared with phacoemulsification alone (very low certainty).

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
RR 1.38 [1.18, 1.63]
2 studies · 239 participants
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Mean change in number of IOP‐lowering drops from baseline · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 282 participants
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Difference in mean IOP from baseline at < 6 months · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 284 participants
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Health‐related quality of life · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IStent in combination with phacoemulsification vs phacoemulsification alone

Intraoperative complications · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found