Findings

What do systematic reviews say?

119 questions · 119 findings · 13 reviews · Headline outcomes only

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No studies found 22 · 18.5%GRADE not reported 2 · 1.7%Very low 18 · 15.1%Low 37 · 31.1%Moderate 34 · 28.6%High 6 · 5%

PEG vs no enteral tube feeding

Survival timea · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 36816 participants
Low

PEG vs no enteral tube feeding

Mortalityc · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 6445 participants
Very low

PEG vs no enteral tube feeding

Quality of life · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PEG vs no enteral tube feeding

Pressure ulcerse · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4421 participants
Moderate

PEG vs no enteral tube feeding

Pain and comfort · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PEG vs no enteral tube feeding

Improvement of nutritional status · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PEG vs placebo

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 101 participants
Low

PEG vs enema alone

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

PEG vs enema alone

S uccessful disimpaction · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG showed no clear difference in S uccessful disimpaction compared with enema (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0 [0.66, 1.51]
1 study · 90 participants
Low

PEG vs paraffin

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 261 participants
Very low

PEG vs flixweed

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 109 participants
Low

PEG vs flixweed

Need for extra treatment · patients aged 0 to 18 years with a diagnosis of functional constipation

It is very uncertain whether PEG changes need for additional therapies compared with flixweed (very low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 3 [1.03, 12.1]
1 study · 109 participants
Very low

PEG vs dietary fibre

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 83 participants
Low

PEG vs dietary fibre

Need for extra treatment · patients aged 0 to 18 years with a diagnosis of functional constipation

It is very uncertain whether PEG changes need for additional therapies compared with dietary fibre (very low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0 [0.05, 5.34]
1 study · 100 participants
Very low

PEG vs dietary fibre

Frequency of faecal incontinence · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 83 participants
Low

PEG vs placebo

Serious adverse events · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0 [0.02, 1.51]
2 studies · 101 participants
Low

PEG vs lactulose

Frequency of defecation (mean number of bowel movements per week) · patients aged 0 to 18 years with a diagnosis of functional constipation

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 465 participants
Very low

PEG vs lactulose

Need for extra treatment · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG may leads to lower need for additional therapies compared with lactulose (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0.5 [0.36, 0.83]
4 studies · 304 participants
Low

PEG vs lactulose

Successful disimpaction · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG may leads to lower successful disimpaction compared with lactulose (low certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0.55 [0.36, 0.83]
1 study · 50 participants
Low

PEG vs lactulose

Adverse events · patients aged 0 to 18 years with a diagnosis of functional constipation

PEG showed no clear difference in adverse events compared with lactulose (moderate certainty).

1 finding from 1 review

Osmotic and stimulant laxatives for the management of childhood constipation 2016 · Cochrane Headline outcomes only
RR 0.8 [0.68, 1.11]
3 studies · 242 participants
Moderate