Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

It is very uncertain whether PCC changes mortality (30‐day) compared with FVIIa (very low certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 1.07 [0.38, 3.03]
3 studies · 278 participants
Very low

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

PCC showed no clear difference in mortality (30‐day) compared with standard treatment (moderate certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 0.53 [0.12, 2.35]
2 studies · 149 participants
Moderate