Wound dehiscence · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw
Hyperbaric oxygen therapy (HBOT) may leads to lower wound dehiscence compared with control without HBOT (low certainty).
1 finding from 1 review
Pain score change at 12 months · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw
1 finding from 1 review
Complete resolution or significant improvement of osteoradionecrosis · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw
Hyperbaric oxygen therapy (HBOT) showed no clear difference in complete resolution or significant improvement of osteoradionecrosis compared with control without HBOT (low certainty).
1 finding from 1 review
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).
1 finding from 1 review
Quality of life · People with established (manifest) MRONJ
1 finding from 1 review
All‐cause mortality · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen leads to lower mortality compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).
1 finding from 1 review
Failure of local tumour control ‐ not reported · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen probably leads to lower failure of local tumour control (local control) compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Local recurrence · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen leads to lower local recurrence (recurrence ) compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).
1 finding from 1 review
Metastasis · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen showed no clear difference in metastasis compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Quality of life ‐ not reported · People undergoing radiation therapy for head and neck cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen probably leads to higher adverse effects compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.75 [0.51, 5.98]
1 study · 18 participants
GRADE not reported
RR 1.78 [0.97, 3.28]
1 study · 46 participants
GRADE not reported
RR 1.94 [1.01, 3.74]
1 study · 45 participants
Very low
Show 2 more findings
Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Metastasis · People undergoing radiotherapy for uterine cervical cancer
Hyperbaric oxygen showed no clear difference in metastasis compared with air breathing (high certainty).
1 finding from 1 review
Quality of life ‐ not reported · People undergoing radiotherapy for uterine cervical cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · People undergoing radiotherapy for uterine cervical cancer
Hyperbaric oxygen leads to higher adverse effects compared with air breathing (high certainty).
1 finding from 1 review
All‐cause mortality · People undergoing radiotherapy for uterine cervical cancer
Hyperbaric oxygen showed no clear difference in mortality compared with air breathing (high certainty).
1 finding from 1 review