Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,809 questions · 1,956 findings · 194 reviews

No studies found 422 · 21.6%GRADE not reported 427 · 21.8%Very low 353 · 18%Low 397 · 20.3%Moderate 293 · 15%High 64 · 3.3%

Oral ciprofloxacin and inhaled colistin vs inhaled tobramycin

Isolation of other micro‐organisms from the respiratory tract: number of positive cultures per patient year · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Oral ciprofloxacin and inhaled colistin vs inhaled tobramycin

Adverse effects of antibiotics: severe cough · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

It is very uncertain whether oral ciprofloxacin and inhaled colistin changes adverse effects of antibiotics: severe cough compared with inhaled tobramycin (TNS) (very low certainty).

1 finding from 1 review

Oral ciprofloxacin and inhaled colistin vs no treatment

Eradication of P aeruginosa from the respiratory tract: proportion of participants with one or more isolates of P aeruginosa from the respiratory tract · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Oral ciprofloxacin and inhaled colistin vs no treatment

Frequency of infective pulmonary exacerbations: number of exacerbations per patient year · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Oral ciprofloxacin and inhaled colistin vs no treatment

Isolation of other micro‐organisms from the respiratory tract: number of positive cultures per patient year · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Oral ivermectin 200 μg/kg (1 to 3 doses) vs topical permethrin 5% cream (1 to 3 applications)

Complete clearance · people with scabies, 2 to 80 years of ageLocation: India, Pakistan

Oral ivermectin 200 μg/kg (1 to 3 doses) may leads to lower complete clearance ‐ week 1 compared with topical permethrin 5% cream (1 to 3 applications) (low certainty).

5 findings from 1 review
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Oral ivermectin 200 μg/kg (1 to 2 doses) vs topical permethrin 5% lotion (1 to 5 applications)

Complete clearance · people with scabies, 5 to 60 years of ageLocation: Egypt, Pakistan

Oral ivermectin 200 μg/kg (1 to 2 doses) showed no clear difference in complete clearance ‐ week 1 ‐ IVER 1 dose versus PER on 5… compared with topical permethrin 5% lotion (1 to 5 applications) (low certainty).

4 findings from 1 review
Show 1 more finding

Oral ivermectin 200 μg/kg (1 to 2 doses) vs topical permethrin 5% lotion (1 to 5 applications)

Number of participants with ≥ 1 AE ‐ week 2 ‐ IVER 2 doses versus PER on 5 consecutive nights · people with scabies, 5 to 60 years of ageLocation: Egypt, Pakistan

It is very uncertain whether oral ivermectin 200 μg/kg (1 to 2 doses) changes number of participants with ≥ 1 AE ‐ week 2 ‐ IVER 2 doses versus… compared with topical permethrin 5% lotion (1 to 5 applications) (very low certainty).

1 finding from 1 review