Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).
2 findings from 1 review
Oral cancer incidence · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer incidence compared with no screening; GRADE not reported.
2 findings from 1 review
Oral health status and oral-care challenges · Children with autism spectrum disorder in Dubai
Two studies found high caries (77%) and gingivitis and considerable oral-care challenges among children with autism spectrum disorder, with low restorative indices (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Jaber et al. reported dental caries in 77% of children with ASD (mean dmft 2.2 in early mixed dentition), gingivitis in all children (generalized 70.4%), mostly poor oral hygiene (59%), and low met-need/restorative…
2 studies
GRADE not reported
Specificity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…
1 finding from 1 review
Summary of findings 4 (no pooled analysis): specificity 0.99 (95% CI 0.99 to 1.00), 1.00 (95% CI 0.91 to 1.00), and 0.72 (95% CI 0.63 to 0.80) across the 3 studies. Certainty VERY LOW.
3 studies · 3600 participants
Very low
Sensitivity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…
1 finding from 1 review
Summary of findings 4 (no pooled analysis): sensitivity 0.85 (95% CI 0.81 to 0.88), 0.82 (95% CI 0.57 to 0.96), and 0.94 (95% CI 0.70 to 1.00) across the 3 studies. Prevalence 12.2% to 30.9%. Certainty VERY LOW.
3 studies · 3600 participants
Very low
Caregivers' preferences for oral hygiene care · Critically ill adults receiving mechanical ventilation in ICU
The review found no eligible studies for this question.
1 finding from 1 review
Plaque · Critically ill adults receiving mechanical ventilation in ICU
1 finding from 1 review
Oral health status (caries, oral hygiene, treatment indices) · Preschool children of incarcerated mothers in UAE prison nurseries
One study found high caries (89.8%) and poor oral hygiene with low restorative care among preschool children of incarcerated mothers (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Al Salami et al. reported caries prevalence of 89.8% (mean dmft 4.97) among preschool children of incarcerated mothers, similar to their counterparts, but worse oral hygiene, higher debris/plaque (93.8% vs 81.8%) and…
1 study
GRADE not reported
Oral health status and treatment needs · Arab children with special health care needs in Ras Al Khaimah
One study found very high caries (85.2%) and high unmet treatment needs among children with special healthcare needs, varying by disability type (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Frequency of hot flushes Oral beta‐estradiol 1.0 and 2.0 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes
1 finding from 1 review
Adverse events Oral beta‐estradiol 1.0 or 2.0 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes
1 finding from 1 review
Hot flush frequency (number/day) · women with hot flushes
Oral beta‐estradiol showed no clear difference in frequency of hot flushes Oral beta‐estradiol 0.5‐1.0 mg/day compared with placebo (low certainty).
1 finding from 1 review
Adverse effects Oral beta‐estradiol 0.5‐2.0 mg/day · women with hot flushes
1 finding from 1 review
Oral mucositis (severe) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
1 finding from 1 review
Oral mucositis (severe). Not estimable - no participants had developed severe oral mucositis by the fourth day after chemotherapy when the data were reported (Zhang 2011, Analysis 4.3, subgroup 3.2); 81 participants in…
1 study · 81 participants
GRADE not reported
Oral mucositis (severe) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
1 finding from 1 review
Oral mucositis (severe). Not estimable - no participants had developed severe oral mucositis by the fourth day after chemotherapy when the data were reported (Zhang 2011, Analysis 4.3, subgroup 3.1); 118 participants…
1 study · 118 participants
GRADE not reported
Oral mucositis (any severity) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (any severity) compared with chlorhexidine rinse (very low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (any severity) compared with low-dose leucovorin rinse (very low certainty).
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (moderate to severe) compared with low-dose leucovorin rinse (very low certainty).
1 finding from 1 review
Oral mucositis (severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (severe) compared with chlorhexidine rinse (very low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin
It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (any severity) compared with high-dose leucovorin rinse (very low certainty).
1 finding from 1 review