Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,809 questions · 1,956 findings · 194 reviews

No studies found 422 · 21.6%GRADE not reported 427 · 21.8%Very low 353 · 18%Low 397 · 20.3%Moderate 293 · 15%High 64 · 3.3%

Dextrose gel vs control

Major neurological disability at 2 years of age (Defined as any of the following: legal blindness, sensorineural deafness requiring hearing aids, moderate or severe cerebral palsy or developmental delay/intellectual impairment (developmental quoti... · newborn infants with hypoglycaemia

Oral dextrose gel showed no clear difference in major neurological disability at age 2 years or olderb Defined as… compared with control (low certainty).

1 finding from 1 review

Dextrose gel vs control

Receipt of intravenous treatment for hypoglycaemia (yes/no) · newborn infants with hypoglycaemia

It is very uncertain whether oral dextrose gel changes receipt of intravenous treatment for hypoglycaemia before discharge… compared with control (very low certainty).

1 finding from 1 review

Dextrose gel vs control

Breastfeeding (exclusive after discharge) ‐ not reported (WHO 2008 definition (yes/no)) · newborn infants with hypoglycaemia

Oral dextrose gel probably leads to higher exclusive breastfeeding after discharge (WHO 2008 definition (yes/no)) compared with control (moderate certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs placebo

Global state: Not improved or worsened ‐ medium term Dichotomised Montgomery‐Asberg Depression Rating Scale (MDRS) · patients with schizophrenia

It is very uncertain whether ORAL FLUPHENAZINE changes global state: Not improved or worsened ‐ medium termDichotomised… compared with PLACEBO (very low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs placebo

Adverse effects: Death ‐ long termOccurrences of death · patients with schizophrenia

ORAL FLUPHENAZINE showed no clear difference in adverse effects: Death ‐ long termOccurrences of death compared with PLACEBO (low certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs placebo

Adverse effects: 2. Extrapyramidal ‐ akathisia · patients with schizophrenia

ORAL FLUPHENAZINE probably leads to higher adverse effects: Extrapyramidal effects (akathisia) ‐ short… compared with PLACEBO (moderate certainty).

1 finding from 1 review

FLUPHENAZINE (ORAL) vs placebo

Adverse effects: extrapyramidal adverse effectsParkinsonism (rigidity) short term (< 3 months) Clinical diagnoses · patients with schizophrenia

ORAL FLUPHENAZINE probably leads to higher adverse effects: Extrapyramidal effects (rigidity) ‐ short… compared with PLACEBO (moderate certainty).

1 finding from 1 review