Secondary outcome: CLASI · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Adverse events: severe · patients with cutaneous disease in systemic lupus erythematosus
Oral methotrexate showed no clear difference in adverse events: severe compared with oral chloroquine (low certainty).
1 finding from 1 review
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral methotrexate may leads to higher adverse events: minor compared with oral chloroquine (low certainty).
1 finding from 1 review
Fall in PTH · patients with bone disease in children with chronic kidney disease
Intermittent oral showed no clear difference in fall in PTH compared with daily oral calcitriol (moderate certainty).
2 findings from 1 review
Kidney function · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
Adverse events ‐ Calcium > 11.5 mg/dL · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
Adverse events ‐ Phosphorus level > 7.5 mg/dL · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
Change in height · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
Plaque · Children and adults with mild to profound ID; setting residential or school
It is very uncertain whether oral hygiene training (toothbrushing routine) of people with ID changes plaque (short term) compared with no oral hygiene training of people with ID (very low certainty).
1 finding from 1 review
Behaviour, attitude and self-efficacy (toothbrushing behaviour) (medium and long term) · Children and adults with mild to profound ID; setting residential or school
1 finding from 1 review
Behaviour, attitude and self-efficacy (steps achieved in a toothbrushing routine), 100 days to 19 months; 59 participants (4 NRS); Very Low. Results not in a format for meta-analysis: 3 NRS (56 participants) reported…
4 studies · 59 participants
Very low
Gingivitis · Children and adults with mild to profound ID; setting residential or school
It is very uncertain whether oral hygiene training (toothbrushing routine) of people with ID changes gingival inflammation (short term) compared with no oral hygiene training of people with ID (very low certainty).
1 finding from 1 review
Length of hospital stay · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Amount of analgesia · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Incidence of systemic infection · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Relief of dysphagia · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Relief of pain · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Patient quality of life · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
The review found no eligible studies for this question.
1 finding from 1 review
None of the studies reported: relief of pain, relief of dysphagia, incidence of systemic infection, amount of analgesia, days stay in hospital, cost of oral care, patient quality of life.
0 studies
No studies found
Plaque · Adults aged 22 to 57 years with mixed levels of ID; setting residential
1 finding from 1 review
Individualised oral care plan vs usual care. Subjective Oral Hygiene Rating scale 1-5 and Improvement Differential, mean 12 months; SOHR 2.97 (intervention) vs 3.10 (control); improvement differential 38% vs 5%; 79…
1 study · 79 participants
Very low
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
Oral steroids showed no clear difference in hearing ‐ return to normal hearing compared with placebo (moderate certainty).
1 finding from 1 review
RR 1.14 [0.97, 1.33]
Studies not reported
Moderate
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate