Findings

What do systematic reviews say?

5 questions · 7 findings · 1 reviews · Movement Disorders

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

RLS symptoms · RLS

2 findings from 1 review

Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 270 participants
Low
Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 276 participants
Low

Drug responders · RLS

Opioids may leads to higher drug responders compared with placebo (low certainty).

2 findings from 1 review

Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
RR 1.82 [1.37, 2.42]
1 study · 276 participants
Low
Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
RR 1.92 [1.49, 2.48]
1 study · 276 participants
Low

Remitters · RLS

Opioids may leads to higher remitters compared with placebo (low certainty).

1 finding from 1 review

Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
RR 2.14 [1.45, 3.16]
1 study · 276 participants
Low

Adverse events · RLS

Opioids may leads to higher adverse Events compared with placebo (low certainty).

1 finding from 1 review

Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
RR 1.22 [1.07, 1.39]
1 study · 304 participants
Low

Quality of life · RLS

1 finding from 1 review

Opioids for restless legs syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 276 participants
Low