Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Epilepsy

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

50% or greater reduction in seizure frequency Number of seizures · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in 50% or greater reduction in seizure frequency Number of seizures compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists as an add‐on therapy for drug‐resistant epilepsy 2013 · Cochrane Headline outcomes only
RR 7.78 [0.46, 130.88]
1 study · 17 participants
Moderate

Treatment withdrawal · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in treatment withdrawal Number of withdrawals compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists as an add‐on therapy for drug‐resistant epilepsy 2013 · Cochrane Headline outcomes only
RR 2.25 [0.25, 20.38]
1 study · 17 participants
Moderate