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What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 9 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 11.1%Moderate 8 · 88.9%High 0 · 0%

Nimodipine vs placebo

Death at the end of · people with acute ischemic stroke

Nimodipine showed no clear difference in death at the end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Recurrence of stroke at the end of · people with acute ischemic stroke

Nimodipine showed no clear difference in recurrence of stroke at the end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Adverse events during treatment period · people with acute ischemic stroke

Nimodipine showed no clear difference in adverse events during treatment period compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Hypotension · people with acute ischemic stroke

Nimodipine showed no clear difference in hypotension during treatment period compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Systolic blood pressure · people with acute ischemic stroke

Nimodipine showed no clear difference in mean systolic blood pressure during or at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Nimodipine vs placebo

Death or dependency at end of · people with acute ischemic stroke

Nimodipine showed no clear difference in death or dependency at end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Death at the end of treatment · people with acute ischemic stroke

Nimodipine showed no clear difference in death at the end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

50% or greater reduction in seizure frequency Number of seizures · patients with drug‐resistant epilepsy

Nimodipine showed no clear difference in 50% or greater reduction in seizure frequency Number of seizures compared with placebo (moderate certainty).

1 finding from 1 review