Nicotine EC probably leads to higher smoking cessation at 6‐12 months compared with non‐nicotine EC (moderate certainty).
Nicotine EC leads to higher smoking cessation at 6 months to 1 year compared with NRT (high certainty).
Nicotine EC may leads to higher smoking cessation at 6 to 12 months Assessed using biochemical… compared with behavioural support only/no support (low certainty).
Fast‐acting nicotine replacement therapy showed no clear difference in smoking cessation compared with nicotine patch (high certainty).
Preloading nicotine replacement therapy (NRT) probably leads to higher smoking cessation compared with standard‐use NRT (moderate certainty).
Nicotine replacement therapy may leads to higher biochemically validated smoking cessation at the latest point in… compared with control (low certainty).
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in smoking cessation (at least six months of compared with NRT alone (low certainty).