Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 24 findings · 4 reviews

No studies found 10 · 41.7%GRADE not reported 4 · 16.7%Very low 3 · 12.5%Low 6 · 25%Moderate 1 · 4.2%High 0 · 0%

Oral NSAIDs vs glucocorticoid injection

Treatment success Fair, good or excellent effectiveness · Adults with lateral elbow pain

It is very uncertain whether oral NSAIDs changes treatment success Fair, good or excellent effectiveness compared with glucocorticoid injection (very low certainty).

1 finding from 1 review

NSAIDs (ketorolac oral rinse; systemic celecoxib) vs placebo or no treatment

Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
  • SoF 3, Clinical resolution (not completely resolved) at 3 months: '1 study evaluated systemic treatment and 1 evaluated topical treatment. Neither found benefit for NSAIDs.' No GRADE. Effects text: celecoxib…
    2 studies
    GRADE not reported

NSAIDs (ketorolac oral rinse; systemic celecoxib) vs placebo or no treatment

Malignant transformation (oral cancer development) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
  • SoF 3 (NSAIDs vs placebo), Cancer development: SoF cell 'Not measured'. Effects text: cancer development was among outcomes in Papadimitrakopoulou 2008 (celecoxib) but did not occur in either arm, probably because of…
    1 study
    GRADE not reported