Findings

What do systematic reviews say?

49 questions · 49 findings · 6 reviews

No studies found 9 · 18.4%GRADE not reported 0 · 0%Very low 22 · 44.9%Low 14 · 28.6%Moderate 1 · 2%High 3 · 6.1%

Serious adverse events · adults with fibromyalgia

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Withdrawals due to adverse events · adults with fibromyalgia

It is very uncertain whether NSAID changes adverse event withdrawal compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.04
4 studies · 230 participants
Very low

Number experiencing adverse effects · adults with fibromyalgia

It is very uncertain whether NSAID changes participants experiencing any adverse event compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.08
4 studies · 230 participants
Very low

Withdrawal (all‐cause) · adults with fibromyalgia

It is very uncertain whether NSAID changes all cause withdrawal compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.03
3 studies · 192 participants
Very low

Death · adults with fibromyalgia

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Relief of pain · women with primary dysmenorrhoea

NSAIDs may leads to higher pain relief dichotomous data compared with placebo (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 4.37 [3.76, 5.09]
Studies not reported
Low

All adverse effects · women with primary dysmenorrhoea

NSAIDs may leads to higher all adverse effects compared with placebo (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 1.29 [1.11, 1.51]
Studies not reported
Low

Relief of pain · women with primary dysmenorrhoea

NSAIDs may leads to higher pain relief dichotomous data compared with paracetamol (low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 1.89 [1.05, 3.43]
Studies not reported
Low

All adverse effects ‐ ibuprofen versus paracetamol · women with primary dysmenorrhoea

It is very uncertain whether NSAIDs changes all adverse effects ‐ ibuprofen versus paracetamol compared with paracetamol (very low certainty).

1 finding from 1 review

Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea 2015 · Cochrane Headline outcomes only
OR 0.85 [0.31, 2.34]
Studies not reported
Very low