Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

49 questions · 49 findings · 6 reviews

No studies found 9 · 18.4%GRADE not reported 0 · 0%Very low 22 · 44.9%Low 14 · 28.6%Moderate 1 · 2%High 3 · 6.1%

NSAIDs vs placebo

Substantial benefit: At least 50% reduction in pain, or PGIC much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes substantial pain relief: at least 50% reduction in pain, or PGIC… compared with placebo (very low certainty).

1 finding from 1 review

NSAIDs vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes moderate pain relief: at least 30% reduction in pain, or PGIC much… compared with placebo (very low certainty).

1 finding from 1 review