What do systematic reviews say?

NPWT vs dressings

It is very uncertain whether NPWT changes wound recurrence compared with dressings (very low certainty).

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 0.5 [0.1, 2.53]
  1 study · 60 participants
  Very low
• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs dressings

NPWT may leads to higher time to healing compared with dressings (low certainty).

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  HR 1.91 [1.21, 2.99]
  1 study · 162 participants
  Low
• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 468 participants
  Low

NPWT 125 mmHg vs NPWT 75 mmHg

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs NPWT 75 mmHg

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with NPWT 75 mmHg (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 1.04 [0.31, 3.51]
  1 study · 251 participants
  Very low

NPWT 125 mmHg vs NPWT 75 mmHg

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs NPWT 75 mmHg

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs NPWT 75 mmHg

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

It is very uncertain whether NPWT 75 mmHg changes wound infection compared with standard care (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.44 [0.17, 1.1]
  1 study · 463 participants
  Very low

NPWT 75 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs usual care

NPWT 125 mmHg showed no clear difference in complete wound healing compared with standard care (moderate certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 1.01 [0.81, 1.27]
  1 study · 460 participants
  Moderate

NPWT 125 mmHg vs usual care

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  Low

NPWT 125 mmHg vs usual care

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with standard care (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.48 [0.2, 1.13]
  4 studies · 596 participants
  Very low

NPWT 125 mmHg vs usual care

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 460 participants
  GRADE not reported

NPWT 125 mmHg vs usual care

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 151 participants
  Very low

NPWT 125 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs usual care

NPWT 125 mmHg showed no clear difference in wound infection compared with standard care (low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.61 [0.31, 1.18]
  2 studies · 509 participants
  Low