Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 2 reviews · Neonatal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 53.8%Moderate 6 · 46.2%High 0 · 0%

NIPPV vs NCPAP

Respiratory failure post extubation · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) probably leads to lower respiratory failure postextubation compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Gastrointestinal perforation · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in gastrointestinal perforation compared with nasal continuous positive airway pressure (NCPAP) (low certainty).

1 finding from 1 review

NIPPV vs NCPAP

Necrotising enterocolitis · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in necrotising enterocolitis compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Chronic lung disease · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in chronic lung disease (oxygen supplementation at 36 weeks) compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Mortality before hospital discharge · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in mortality (defined as death before discharge) compared with nasal continuous positive airway pressure (NCPAP) (low certainty).

1 finding from 1 review

NIPPV vs NCPAP

Need for endotracheal tube ventilation · )

Nasal intermittent positive pressure ventilation (NIPPV) probably leads to lower need for endotracheal tube ventilation compared with nasal continuous positive airway pressure (NCPAP) (by population) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · )

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in severe intraventricular hemorrhage (grade III/IV) compared with nasal continuous positive airway pressure (NCPAP) (by population) (low certainty).

1 finding from 1 review