Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 38 findings · 6 reviews

No studies found 13 · 34.2%GRADE not reported 0 · 0%Very low 6 · 15.8%Low 17 · 44.7%Moderate 2 · 5.3%High 0 · 0%

N‐acetylcysteine vs placebo

Efficacy: number of participants who respond to treatment ‐ at 3 months · adults (aged 18 years+) with depression in bipolar disorder

N‐acetylcysteine showed no clear difference in efficacy: number of participants who respond to treatment ‐ at 3… compared with placebo (low certainty).

1 finding from 1 review