What do systematic reviews say?

1 year · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 1 year

2.7 years (31 months median) · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 2.7 years (31 months median)

2 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 2 years

6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Microbiological assessment: quantitative (culture/CFU counting)

3.5 years (42 months) · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 3.5 years (42 months)

6 months · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 6 months

6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Microbiological assessment: semi-quantitative (Dentocult/commercial kit)