Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%

Mortality: prone position vs supine

Longer‐term mortality (LTM)Alive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in longer‐term mortality (LTM)Alive or dead compared with supine (low certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.86 [0.72, 1.03]
8 studies · 2141 participants
Low

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.77 [0.65, 0.92]
7 studies · 977 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: lower tidal volume ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: lower tidal volume… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.73 [0.55, 0.96]
5 studies · 911 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.85 [0.71, 1.01]
8 studies · 1758 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.77 [0.61, 0.99]
5 studies · 1005 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours after entry criteria/ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.75 [0.59, 0.94]
5 studies · 1024 participants
Moderate