What do systematic reviews say?

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Moderate vs low protein concentration of human milk fortifier

Moderate showed no clear difference in mortality during the intervention period compared with low protein concentration of human milk fortifier; GRADE not reported.

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  RR 0.48 [0.05, 5.17]
  1 study · 112 participants
  GRADE not reported

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 176 participants
  Very low

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 217 participants
  Low

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 217 participants
  Very low

Inhaled NO at moderate vs severe criteria

Inhaled NO at moderate showed no clear difference in use of ECMO before hospital discharge compared with severe criteria (moderate certainty).

• Nitric oxide for respiratory failure in infants born at or near term 2017 · Cochrane Headline outcomes only
  RR 1.01 [0.66, 1.54]
  4 studies · 439 participants
  Moderate

Inhaled NO at moderate vs severe criteria

Inhaled NO at moderate probably leads to lower progression to severe criteria compared with severe criteria (moderate certainty).

• Nitric oxide for respiratory failure in infants born at or near term 2017 · Cochrane Headline outcomes only
  RR 0.66 [0.55, 0.79]
  6 studies · 512 participants
  Moderate

Inhaled NO at moderate vs severe criteria

Inhaled NO at moderate showed no clear difference in neurodevelopmental disability at 18 to 24 months among survivors compared with severe criteria (moderate certainty).

• Nitric oxide for respiratory failure in infants born at or near term 2017 · Cochrane Headline outcomes only
  RR 1.13 [0.74, 1.74]
  1 study · 234 participants
  Moderate

Inhaled NO at moderate vs severe criteria

Inhaled NO at moderate showed no clear difference in death or requirement for ECMO compared with severe criteria (low certainty).

• Nitric oxide for respiratory failure in infants born at or near term 2017 · Cochrane Headline outcomes only
  RR 0.88 [0.62, 1.27]
  5 studies · 495 participants
  Low

Inhaled NO at moderate vs severe criteria

Inhaled NO at moderate showed no clear difference in death before hospital discharge compared with severe criteria (moderate certainty).

• Nitric oxide for respiratory failure in infants born at or near term 2017 · Cochrane Headline outcomes only
  RR 0.69 [0.38, 1.26]
  5 studies · 495 participants
  Moderate