Oral misoprostol showed no clear difference in apgar score less than 7 at 5 minutes compared with mechanical methods (low certainty).
Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with mechanical methods (low certainty).
Oral misoprostol probably leads to lower oxytocin augmentation compared with placebo/no treatment (moderate certainty).
It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with placebo/no treatment (very low certainty).
It is very uncertain whether oral misoprostol changes apgar score less than 7 at 5 minutes compared with placebo/no treatment (very low certainty).
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with vaginal dinoprostone (low certainty).
Oral misoprostol probably leads to lower caesarean section compared with vaginal dinoprostone (moderate certainty).
It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes women not using/receiving misoprostol at birth compared with usual (or standard) care (very low certainty).
It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes inappropriate use (or misuse) of misoprostol compared with usual (or standard) care (very low certainty).
Sublingual misoprostol showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).
Sublingual misoprostol showed no clear difference in nausea compared with vaginal misoprostol (moderate certainty).
Sublingual misoprostol showed no clear difference in women's dissatisfaction with the procedure compared with vaginal misoprostol (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes vaginal birth within 24 hours compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes caesarean section compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes oxytocin augmentation compared with oral misoprostol four‐ to six‐hourly (very low certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes uterine hyperstimulation without fetal heart rate changes compared with oral misoprostol four‐ to six‐hourly (very low certainty).