Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Pain, Palliative and Supportive Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with cancer pain

Methadone may leads to higher participant‐reported pain intensity compared with morphine (low certainty).

1 finding from 1 review

Methadone for cancer pain 2017 · Cochrane Headline outcomes only
OR 76
103 participants
Low

Adverse events: appetite, thirst, somnolence · people with cancer pain

1 finding from 1 review

Methadone for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 342 participants
Very low