Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

50 questions · 50 findings · 8 reviews · Headline outcomes only

No studies found 11 · 22%GRADE not reported 0 · 0%Very low 17 · 34%Low 19 · 38%Moderate 3 · 6%High 0 · 0%

Modified personal protective equipment (PPE): mask plus tabs vs standard masks

Contamination of mask from hands · healthcare workers

It is very uncertain whether modified personal protective equipment (PPE): mask plus tabs changes contamination of mask from hands compared with standard masks (very low certainty).

1 finding from 1 review

Mask vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

Face mask may leads to lower treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (low certainty).

1 finding from 1 review

Medical/surgical masks vs no masks

Viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 · general population

Medical/surgical masks showed no clear difference in viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 compared with no masks (moderate certainty).

1 finding from 1 review

Modified personal protective equipment (PPE): mask plus tabs vs standard masks

Contamination of head from hands · healthcare workers

It is very uncertain whether modified personal protective equipment (PPE): mask plus tabs changes contamination of head from hands compared with standard masks (very low certainty).

1 finding from 1 review

LMA vs endotracheal tube (ETT)

Tally of participants with one or more serious adverse event(s) during procedure or within 24 hours after procedure · critically ill adults undergoing percutaneous dilatational tracheostomy

It is very uncertain whether laryngeal mask airway (LMA) changes tally of participants with one or more serious adverse event(s)… compared with endotracheal tube (ETT) (very low certainty).

1 finding from 1 review

LMA vs endotracheal tube (ETT)

Failure of procedure requiring conversion · critically ill adults undergoing percutaneous dilatational tracheostomy

Laryngeal mask airway (LMA) may leads to higher failure of procedure, requiring conversion to any other procedure compared with endotracheal tube (ETT) (low certainty).

1 finding from 1 review

Nasal interfaces (single nasal prong, binasal prongs (long or short), or nasal masks) vs face mask

Mortality before hospital discharge · term and preterm infants resuscitated at birth, using positive pressure ventilation

Nasal interfaces (single nasal prong, binasal prongs (long or… showed no clear difference in death before discharge compared with face mask (low certainty).

1 finding from 1 review

Nasal interfaces (single nasal prong, binasal prongs (long or short), or nasal masks) vs face mask

Intubation and mechanical ventilation in the DR · term and preterm infants resuscitated at birth, using positive pressure ventilation

It is very uncertain whether nasal interfaces (single nasal prong, binasal prongs (long or… changes intubation and mechanical ventilation in the DR compared with face mask (very low certainty).

1 finding from 1 review

Nasal interfaces (single nasal prong, binasal prongs (long or short), or nasal masks) vs face mask

Intubation and mechanical ventilationwithin 24 hours of birth · term and preterm infants resuscitated at birth, using positive pressure ventilation

It is very uncertain whether nasal interfaces (single nasal prong, binasal prongs (long or… changes intubation and mechanical ventilationwithin 24 hours of birth compared with face mask (very low certainty).

1 finding from 1 review