Manipulative therapy vs control condition
Change in daily hours of crying Crying diary completed by parents · infants with colic defined by recognised criteria
1 finding from 1 review
- no estimate extracted5 studies · 223 participantsLow
Findings
What do systematic reviews say?
35 questions · 50 findings · 3 reviews
No studies found 0 · 0%GRADE not reported 6 · 12%Very low 15 · 30%Low 15 · 30%Moderate 6 · 12%High 8 · 16%
Manipulative therapy vs control condition
Presence/absence of colic Global impression of change scale completed by parents · infants with colic defined by recognised criteria
Manipulative therapy showed no clear difference in presence/absence of colic Global impression of change scale… compared with control condition (low certainty).
1 finding from 1 review
- OR 11.12 [0.46, 267.52]3 studies · 185 participantsLow
Manipulative therapy vs control condition
Adverse events Incidents reported by parents · infants with colic defined by recognised criteria
1 finding from 1 review
- no estimate extracted1 study · 102 participantsGRADE not reported
Spinal manipulative therapy vs other interventions
Overall Pain ‐ 1 to 2 weeks (adequate allocation concealment, and blinding) visual analogue scale; 1 to 9 points (higher indicates worse pain) · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted3 studies · 383 participantsLow
Spinal manipulative therapy vs inert interventions
Pain at 3 to 6 months Scale from: 0 (no pain) to 10 (worse pain) · Patients with acute low‐back pain
2 findings from 1 review
- no estimate extracted3 studies · 311 participantsLow
- no estimate extracted1 study · 178 participantsLow
Spinal manipulative therapy vs inert interventions
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. · Patients with acute low‐back pain
2 findings from 1 review
- no estimate extracted2 studies · 205 participantsModerate
- no estimate extracted1 study · 178 participantsLow
Spinal manipulative therapy vs inert interventions
Recovery at one week · Patients with acute low‐back pain
Spinal manipulative therapy showed no clear difference in recovery at one week compared with inert interventions (low certainty).
1 finding from 1 review
- RR 0.96 [0.5, 1.85]2 studies · 263 participantsLow
Spinal manipulative therapy vs inert interventions
Serious adverse events · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted2 studies · 2 participantsGRADE not reported
Spinal manipulative therapy vs other interventions
Reduction in pain intensity · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted3 studies · 606 participantsModerate
Spinal manipulative therapy vs other interventions
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. · Patients with acute low‐back pain
2 findings from 1 review
- no estimate extracted1 study · 241 participantsLow
- no estimate extracted3 studies · 681 participantsModerate
Spinal manipulative therapy vs other interventions
Recovery at one month · Patients with acute low‐back pain
Spinal manipulative therapy showed no clear difference in recovery at one month compared with other interventions (low certainty).
1 finding from 1 review
- RR 1.06 [0.94, 1.21]2 studies · 117 participantsLow
Spinal manipulative therapy vs other interventions
Serious adverse events · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted2 studies · 2 participantsGRADE not reported
Spinal manipulative therapy vs inert interventions
Pain VAS 0‐100 (higher means worse) · adults with chronic low‐back pain
2 findings from 1 review
- no estimate extracted1 study · 72 participantsVery low
- no estimate extracted1 study · 70 participantsVery low
Spinal manipulative therapy vs other interventions
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with chronic low‐back pain
3 findings from 1 review
- no estimate extracted6 studies · 1405 participantsHigh
- no estimate extracted5 studies · 1074 participantsModerate
- no estimate extracted3 studies · 1285 participantsHigh
Spinal manipulative therapy vs other interventions
Functional ability · adults with chronic low‐back pain
2 findings from 1 review
- no estimate extracted6 studies · 1402 participantsHigh
- no estimate extracted6 studies · 1323 participantsModerate
Spinal manipulative therapy vs other interventions
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. · adults with chronic low‐back pain
1 finding from 1 review
- no estimate extracted4 studies · 1418 participantsHigh
Spinal manipulative therapy vs other interventions
Recovery at one month · adults with chronic low‐back pain
Spinal manipulative therapy probably leads to higher recovery at 1 month compared with all other interventions (moderate certainty).
1 finding from 1 review
- RR 1.2 [1.04, 1.37]3 studies · 370 participantsModerate
Spinal manipulative therapy vs inert interventions
Recovery at one month · adults with chronic low‐back pain
It is very uncertain whether spinal manipulative therapy changes recovery at 1 month compared with inert interventions (very low certainty).
2 findings from 1 review
- RR 1.03 [0.49, 2.19]1 study · 72 participantsVery low
- RR 0.96 [0.56, 1.65]1 study · 70 participantsVery low
Spinal manipulative therapy vs sham SMT
Reduction in pain intensity · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted1 study · 74 participantsVery low
Spinal manipulative therapy vs sham SMT
Functional status at one month Oswestry Disability Index. Scale from: 0 (no dysfunction) to 100 (worse function) · Patients with acute low‐back pain
1 finding from 1 review
- no estimate extracted1 study · 94 participantsVery low