Adverse events (ITT analysis) · group A streptococcal pharyngitis
Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Serious adverse events · adults and adolescents with scrub typhus
1 finding from 1 review
Treatment failure · adults and adolescents with scrub typhus
It is very uncertain whether macrolides changes treatment failure compared with doxycycline (very low certainty).
1 finding from 1 review
Resolution of fever within 48 hours · adults and adolescents with scrub typhus
It is very uncertain whether macrolides changes resolution of fever within 48 hours compared with doxycycline (very low certainty).
1 finding from 1 review
Resolution of fever within 5 days · adults and adolescents with scrub typhus
Macrolides showed no clear difference in resolution of fever within 5 days compared with doxycycline (low certainty).
1 finding from 1 review
Time to defervescence · adults and adolescents with scrub typhus
1 finding from 1 review
Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID
It is very uncertain whether regimens containing macrolides (azithromycin) changes clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (very low certainty).
2 findings from 1 review
RR 1.18 [0.89, 1.55]
Studies not reported
Very low
RR 1.35 [1.1, 1.67]
Studies not reported
Moderate
Clinical cure according to criteria established by study authors Severe PID · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (low certainty).
1 finding from 1 review
RR 1 [0.96, 1.05]
Studies not reported
Low
Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).
1 finding from 1 review
RR 0.71 [0.38, 1.34]
Studies not reported
Low
Microbiological clearance · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in microbiological clearance compared with regimens containing tetracycline (doxycycline); GRADE not reported.
1 finding from 1 review
RR 1.02 [0.98, 1.06]
Studies not reported
GRADE not reported
Laparoscopic evidence of resolution of PID based on physician opinion · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of stay · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fertility outcome · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found