Total mortality · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total mortality compared with standard blood pressure targets (moderate certainty).
1 finding from 1 review
Total serious adverse events · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total serious adverse events compared with standard blood pressure targets (low certainty).
1 finding from 1 review
Cardiovascular events · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total cardiovascular events compared with standard blood pressure targets (low certainty).
1 finding from 1 review
Cardiovascular mortality · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in cardiovascular mortality compared with standard blood pressure targets (moderate certainty).
1 finding from 1 review
Withdrawals due to adverse events · cardiovascular disease with high blood pressure
It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty).
1 finding from 1 review
Total mortality · adult patients with hypertension
Lower BP target showed no clear difference in total mortality compared with standard BP target (high certainty).
1 finding from 1 review
RR 0.95 [0.86, 1.05]
Studies not reported
High
Total serious adverse events№ of participants: 18165(6 RCTs) · adult patients with hypertension
Lower BP target showed no clear difference in total serious adverse events№ of participants: 18165(6 RCTs) compared with standard BP target (moderate certainty).
1 finding from 1 review
RR 1.04 [0.99, 1.08]
Studies not reported
Moderate
Myocardial infarction · adult patients with hypertension
Lower BP target may leads to lower myocardial infarction№ of participants: 38,198(8 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.84 [0.73, 0.96]
Studies not reported
Low
Stroke · adult patients with hypertension
Lower BP target showed no clear difference in stroke№ of participants: 37,087(7 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.88 [0.77, 1.01]
Studies not reported
Low
Congestive heart failure · adult patients with hypertension
Lower BP target may leads to lower congestive heart failure№ of participants: 15,859(5 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.75 [0.6, 0.92]
Studies not reported
Low
Other serious adverse events · adult patients with hypertension
Lower BP target may leads to higher other serious adverse events compared with standard BP target (low certainty).
1 finding from 1 review
RR 1.44 [1.32, 1.59]
Studies not reported
Low