Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

59 questions · 68 findings · 17 reviews

No studies found 1 · 1.5%GRADE not reported 21 · 30.9%Very low 11 · 16.2%Low 17 · 25%Moderate 7 · 10.3%High 11 · 16.2%

Transfer from incubator to cot at lower vs higher body weight

Proportion of infants having at least one episode of low temperature requiring overhead heater use · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of low temperature… compared with higher body weight (high certainty).

1 finding from 1 review

Transfer from incubator to cot at lower vs higher body weight

Proportion of infants having at least one episode of returning to incubator · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of returning to… compared with higher body weight (moderate certainty).

1 finding from 1 review

Transfer from incubator to cot at lower vs higher body weight

Breastfeeding (exclusive at discharge) · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants exclusive breastfeeding at discharge compared with higher body weight (high certainty).

1 finding from 1 review

Lower unemployment rate vs Higher unemployment rate (low <=5% / medium >5-10% / high >10%)

Caries experience (mean DMFT) · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)

Mean DMFT tended to increase with unemployment rate (low 1.23, medium 2.08, high 2.38; ANOVA p<.05); descriptive country-level means only, not meta-analyzed or GRADE-rated.

3 findings from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: risk of spontaneous rescue‐free bowel movements in the short terma · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in laxation response: risk of spontaneous rescue‐free bowel… compared with higher dose (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: risk of spontaneous rescue‐free bowel movements in the medium termb · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

It is very uncertain whether methylnaltrexone lower dose changes laxation response: risk of spontaneous rescue‐free bowel… compared with higher dose (very low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: patient assessment of change in bowel status at the end of trial · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in laxation response: patient assessment of change in bowel statusgat… compared with higher dose (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Symptoms of opioid withdrawal in the medium term · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in symptoms of opioid withdrawal in the medium term compared with higher dose (low certainty).

1 finding from 1 review