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Evidence found and GRADE certainty

72 questions · 82 findings · 19 reviews

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No studies found 2 · 2.4%GRADE not reported 21 · 25.6%Very low 16 · 19.5%Low 19 · 23.2%Moderate 13 · 15.9%High 11 · 13.4%

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Severe intraventricular haemorrhage · preterm infants

Lower showed no clear difference in severe intraventricular haemorrhage (grade 3 or 4) compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

1 finding from 1 review

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Necrotising enterocolitis · preterm infants

Lower showed no clear difference in necrotising enterocolitis compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

1 finding from 1 review

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Chronic lung disease · preterm infants

It is very uncertain whether lower changes chronic lung disease (36 weeks' corrected age) compared with higher oxygen concentrations titrated to target oxygen saturations… (very low certainty).

1 finding from 1 review

Lower vs higher cumulative dose dexamethasone regimen

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants at risk for bronchopulmonary dysplasia

Lower showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks PMA compared with higher cumulative dose dexamethasone regimen (low certainty).

1 finding from 1 review

Lower vs higher cumulative dose dexamethasone regimen

Death or cerebral palsy at 1 to 3 years · preterm infants at risk for bronchopulmonary dysplasia

Lower showed no clear difference in death or cerebral palsy at 1 to 3 years compared with higher cumulative dose dexamethasone regimen (low certainty).

1 finding from 1 review

Lower vs higher cumulative dose dexamethasone regimen

Death or abnormal neurodevelopmental outcome (various definitions) · preterm infants at risk for bronchopulmonary dysplasia

It is very uncertain whether lower changes death or abnormal neurodevelopmental outcome (various definitions)… compared with higher cumulative dose dexamethasone regimen (very low certainty).

1 finding from 1 review

Transfer from incubator to cot at lower vs higher body weight

Proportion of infants having at least one episode of low temperature requiring overhead heater use · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of low temperature… compared with higher body weight (high certainty).

1 finding from 1 review

Transfer from incubator to cot at lower vs higher body weight

Proportion of infants having at least one episode of returning to incubator · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of returning to… compared with higher body weight (moderate certainty).

1 finding from 1 review

Transfer from incubator to cot at lower vs higher body weight

Breastfeeding (exclusive at discharge) · patients with preterm infants

Transfer from incubator to cot at lower showed no clear difference in proportion of infants exclusive breastfeeding at discharge compared with higher body weight (high certainty).

1 finding from 1 review