It is very uncertain whether late (seven days or more following birth) higher changes hypernatraemia (≥ 150 mmol/L) compared with lower sodium intake (very low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 7.88 [0.43, 144.81]
2 studies · 69 participants
Very low

Late (seven days or more following birth) higher vs lower sodium intake

Postnatal growth failure (weight < 10th percentile) · preterm or low birth weight infants

Late (seven days or more following birth) higher may leads to lower postnatal growth failure (weight < 10th percentile) compared with lower sodium intake (low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 0.25 [0.09, 0.69]
1 study · 29 participants
Low

Late (seven days or more following birth) higher vs lower sodium intake

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether late (seven days or more following birth) higher changes necrotising enterocolitis compared with lower sodium intake (very low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 0.07 [0, 1.25]
1 study · 49 participants
Very low

Late (seven days or more following birth) higher vs lower sodium intake

Chronic lung disease · preterm or low birth weight infants

It is very uncertain whether late (seven days or more following birth) higher changes chronic lung disease compared with lower sodium intake (very low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 2.03 [0.8, 5.2]
1 study · 49 participants
Very low

Late (seven days or more following birth) higher vs lower sodium intake

Mortality Mortality at latest · preterm or low birth weight infants

It is very uncertain whether late (seven days or more following birth) higher changes mortality (latest time reported up to hospital discharge) compared with lower sodium intake (very low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 0.13 [0.01, 2.2]
1 study · 49 participants
Very low

Late (seven days or more following birth) higher vs lower sodium intake

Neurodevelopmental disability · preterm or low birth weight infants

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Early (less than seven days following birth) higher vs lower sodium intake

Mortality Mortality at latest · preterm or low birth weight infants

Early (less than seven days following birth) higher showed no clear difference in mortality (latest time reported up to hospital discharge) compared with lower sodium intake (low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 1.02 [0.38, 2.72]
3 studies · 83 participants
Low

Early (less than seven days following birth) higher vs lower sodium intake

Neurodevelopmental disability · preterm or low birth weight infants

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Early (less than seven days following birth) higher vs lower sodium intake

Hyponatraemia (< 130 mmol/L) · preterm or low birth weight infants

Early (less than seven days following birth) higher showed no clear difference in hyponatraemia (< 130 mmol/L) compared with lower sodium intake (low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 0.68 [0.4, 1.13]
3 studies · 83 participants
Low

Early (less than seven days following birth) higher vs lower sodium intake

Hypernatraemia (≥ 150 mmol/L) · preterm or low birth weight infants

Early (less than seven days following birth) higher showed no clear difference in hypernatraemia (≥ 150 mmol/L) compared with lower sodium intake (low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 1.62 [1, 2.65]
4 studies · 103 participants
Low

Early (less than seven days following birth) higher vs lower sodium intake

Postnatal growth failure · preterm or low birth weight infants

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Early (less than seven days following birth) higher vs lower sodium intake

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether early (less than seven days following birth) higher changes necrotising enterocolitis compared with lower sodium intake (very low certainty).

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
RR 4.6 [0.23, 90.84]
1 study · 46 participants
Very low

Early (less than seven days following birth) higher vs lower sodium intake

Chronic lung disease · preterm or low birth weight infants

1 finding from 1 review

Higher versus lower sodium intake for preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Anticipated low‐responders: higher vs lower dose of FSH

300/450 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 300/450 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… 2024 · Cochrane Headline outcomes only
OR 1.2 [0.78, 1.86]
3 studies · 538 participants
Low

Anticipated low‐responders: higher vs lower dose of FSH

400/450 IU vs 300 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 400/450 IU vs 300 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… 2024 · Cochrane Headline outcomes only
OR 0.77 [0.19, 3.19]
1 study · 62 participants
Low