Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride toothpaste 550 ppm (lower concentration) probably leads to lower fluorosis (percentage prevalence in permanent teeth) compared with fluoride toothpaste 1000 ppm (higher concentration) (moderate certainty).
1 finding from 1 review
White spot lesion incidence · High caries-risk patients: fixed-orthodontic-appliance patients and children with partially erupted permanent molars
Low-power CO2 laser (LLLT) is associated with a lower incidence of new white spot lesions than placebo (OR 0.21, CI 0.15 to 0.30; ungraded, 3 RCTs, considerable heterogeneity I2=71%).
1 finding from 1 review
Caries increment, surface index D(M)FS · Children with high risk of dental decay
It is very uncertain whether slow-release fluoride device (fluoride glass beads) changes increase in DMFS at 2 years compared with baseline compared with placebo or usual care (control) (very low certainty).
1 finding from 1 review
Caries increment, tooth index D(M)FT · Children with high risk of dental decay
It is very uncertain whether slow-release fluoride device (fluoride glass beads) changes increase in DMFT at 2 years compared with baseline compared with placebo or usual care (control) (very low certainty).
1 finding from 1 review
Progression of caries lesion into enamel or dentine · Children with high risk of dental decay
The review found no eligible studies for this question.
1 finding from 1 review
No evidence found
0 studies
No studies found
Dental pain due to decay · Children with high risk of dental decay
The review found no eligible studies for this question.
1 finding from 1 review
No evidence found
0 studies
No studies found
Retention of slow-release fluoride devices (devices staying intact) · Children with high risk of dental decay
1 finding from 1 review
Harms of slow-release fluoride devices · Children with high risk of dental decay
1 finding from 1 review
Use of healthcare resources (cost effectiveness, time taken to fit, number of dental visits) · Children with high risk of dental decay
The review found no eligible studies for this question.
1 finding from 1 review
Participant satisfaction · Children with high risk of dental decay
The review found no eligible studies for this question.
1 finding from 1 review
No RCT evidence found
0 studies
No studies found
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Salivary cortisol, cariogenic bacterial load and dental caries · Kindergarten-age children
In one cross-sectional study of children, low socioeconomic status, higher basal salivary cortisol and higher cariogenic bacterial counts were each independently associated with higher dental caries risk; not pooled (ungraded).
1 finding from 1 review
Weight (kg) · Adults or children with overweight or obesity
1 finding from 1 review
Body‐mass index (BMI) · Adults or children with overweight or obesity
1 finding from 1 review
Adverse events (n/N) · Adults or children with overweight or obesity
1 finding from 1 review
Health‐related quality of life Scale · Adults or children with overweight or obesity
1 finding from 1 review
All‐cause mortality · Adults or children with overweight or obesity
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with WHO grade 3 or 4 bleeding up to 30 days from study entry · People with a haematological disorder
Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in number of participants with WHO grade 3 or 4 bleeding up to 30 days… compared with high‐dose schedule (low certainty).
1 finding from 1 review
Time to first bleeding episode (days) · People with a haematological disorder
1 finding from 1 review
Mortality from all causes up to 30 days from study entry · People with a haematological disorder
Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with high‐dose schedule (low certainty).
1 finding from 1 review