Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

150 questions · 151 findings · 13 reviews

No studies found 42 · 27.8%GRADE not reported 8 · 5.3%Very low 52 · 34.4%Low 29 · 19.2%Moderate 16 · 10.6%High 4 · 2.6%

'Magic' mouthwash (lidocaine, diphenhydramine, aluminium hydroxide) vs Salt and soda mouthwash

Time to heal mucositis (days) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

'Magic' mouthwash (lidocaine, diphenhydramine, aluminium hydroxide) showed no clear difference in time to heal mucositis (days) compared with salt and soda mouthwash; GRADE not reported.

1 finding from 1 review

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of lidocaine intraperitoneal instillation plus… may leads to lower number of women requiring rescue medication compared with intramuscular morphine alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Two pumps of 10% cervical lidocaine spray and paracervical block vs two pumps of cervical normal saline spray and paracervical block

Pain with dilation ‐ not measured · people requesting a surgical abortion at seven weeks' gestation or less

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Two pumps of 10% cervical lidocaine spray and paracervical block vs two pumps of cervical normal saline spray and paracervical block

Pain with aspiration ‐ not measured · people requesting a surgical abortion at seven weeks' gestation or less

The review found no eligible studies for this question.

1 finding from 1 review

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs placebo

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of intraperitoneal lidocaine instillation and… may leads to lower number of women requiring rescue medication compared with placebo (low certainty).

1 finding from 1 review