Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
It is very uncertain whether lidocaine instillation changes adverse events within 48 hours post operation compared with placebo (very low certainty).
1 finding from 1 review
RR 1.04 [0.4, 2.69]
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Lidocaine instillation may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.27 [0.17, 0.44]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).
1 finding from 1 review
RR 0.5 [0.1, 2.43]
Studies not reported
Low
Intraoperative pain or discomfort (continuous data) · adults undergoing phacoemulsification cataract surgery
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery
Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).
1 finding from 1 review
OR 0.4 [0.29, 0.57]
Studies not reported
Moderate
Discomfort/pain · adults undergoing phacoemulsification cataract surgery
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Participant satisfaction · adults undergoing phacoemulsification cataract surgery
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Need for additional anaesthesia during surgery Assessed dichotomously, as 'additional anaesthesia given' or 'additional anaesthesia not given' · adults undergoing phacoemulsification cataract surgery
Topical anaesthesia plus intracameral lidocaine showed no clear difference in need for additional anaesthesia during surgery Assessed… compared with topical anaesthesia alone (low certainty).
1 finding from 1 review
OR 0.88 [0.56, 1.39]
Studies not reported
Low
Mean change of endothelial cell loss · adults undergoing phacoemulsification cataract surgery
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery
Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).
1 finding from 1 review
OR 1 [0.32, 3.16]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).
1 finding from 1 review
RR 0.22 [0.09, 0.54]
Studies not reported
Low
Pain at 48 hours (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction
Topical anaesthetic gel (prilocaine-lidocaine) showed no clear difference in pain at 48 hours (VAS 0-10) compared with eugenol; GRADE not reported.
1 finding from 1 review
Pain with aspirationa,b · people requesting a surgical abortion in the first trimester
1 finding from 1 review
Pain with dilation ‐ not measured · people requesting a surgical abortion in the first trimester
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain during procedure ‐ not measured · people requesting a surgical abortion in the first trimester
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found