Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 5 · 100%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse · Live birth rate
  Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
  OR 1.72 [1.4, 2.11]
  11 studies · 2060 participants
  High
Direct match · question page
- Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse · Clinical pregnancy rate
  Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
  OR 1.69 [1.45, 1.98]
  23 studies · 3321 participants
  High
Direct match · question page
- Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse · Multiple pregnancy rate
  Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
  OR 0.74 [0.42, 1.32]
  14 studies · 2247 participants
  High
Related · question page
- Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse · Ovarian hyperstimulation syndrome rate
  Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1848 participants
  High
Related · question page
- Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse · Miscarriage rate per pregnancy
  Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
  OR 0.94 [0.66, 1.32]
  15 studies · 736 participants
  High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Live birth rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts leads to higher live birth rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 1.72 [1.4, 2.11]
11 studies · 2060 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

OHSS · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in ovarian hyperstimulation syndrome rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1848 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Clinical pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts leads to higher clinical pregnancy rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 1.69 [1.45, 1.98]
23 studies · 3321 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Miscarriage · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in miscarriage rate per pregnancy compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 0.94 [0.66, 1.32]
15 studies · 736 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Multiple pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in multiple pregnancy rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 0.74 [0.42, 1.32]
14 studies · 2247 participants
High