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Evidence found and GRADE certainty

164 questions · 176 findings · 17 reviews

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No studies found 48 · 27.3%GRADE not reported 21 · 11.9%Very low 87 · 49.4%Low 16 · 9.1%Moderate 4 · 2.3%High 0 · 0%

In-office laser therapy (all types combined) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through air blast stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

It is very uncertain whether in-office laser therapy (all types combined) changes changes in intensity of pain (VAS 0 to 10) tested through air blast… compared with placebo (placebo laser or placebo agent) or no treatment (very low certainty).

3 findings from 1 review

In-office laser therapy (all types combined) vs Placebo (placebo laser or placebo agent) or no treatment

Adverse events · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation
2 findings from 1 review

In-office laser therapy (all types combined) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through tactile stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

It is very uncertain whether in-office laser therapy (all types combined) changes changes in intensity of pain (VAS 0 to 10) tested through tactile… compared with placebo (placebo laser or placebo agent) or no treatment (very low certainty).

3 findings from 1 review

Low‐level laser therapy vs Control (no laser device used)

Maximum pain (verbal rating scale, VRS) · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether low energy level laser therapy (LLLT) changes maximum pain (verbal rating scale, VRS) compared with control (no laser device used) (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐ patient self‐assessment of good to excellent scar improvement ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ regrowth ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ pain related to treatment ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ hyperpigmentation ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ depigmentation ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ purpura ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus verapamil versus verapamil ‐ total ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes incidence of treatment‐related adverse effects ‐ 595‐nm PDL plus… compared with other treatment (very low certainty).

1 finding from 1 review