Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Epilepsy

No studies found 2 · 50%GRADE not reported 0 · 0%Very low 1 · 25%Low 0 · 0%Moderate 1 · 25%High 0 · 0%

Seizure freedom · absence seizures in children and adolescents

1 finding from 1 review

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 405 participants
Moderate

80% or greater reduction in seizure frequency ‐ not reported · absence seizures in children and adolescents

The review found no eligible studies for this question.

1 finding from 1 review

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

50% or greater reduction in seizure frequency · absence seizures in children and adolescents

The review found no eligible studies for this question.

1 finding from 1 review

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Normalisation of the EEG ‐ not reported · absence seizures in children and adolescents

It is very uncertain whether lamotrigine changes normalisation of the EEG compared with valproate (very low certainty).

1 finding from 1 review

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents 2021 · Cochrane Headline outcomes only
RR 2.39 [1.14, 5.04]
1 study · 45 participants
Very low