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What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 3 reviews · Pregnancy and Childbirth

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 4.8%Low 6 · 28.6%Moderate 8 · 38.1%High 6 · 28.6%

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal composite morbidity · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal composite morbidity compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Endomyometritis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal endomyometritis compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Wound infection · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal wound Infection compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal UTI/cystitis/pyelonephritis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal UTI/cystitis/pyelonephritis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal respiratory infection (pneumonia) · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal respiratory infection (pneumonia) compared with after neonatal umbilical cord clamping (low certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Neonatal sepsis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal sepsis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Admission to neonatal intensive care unit · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal ICU admission compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Intravenous/intramuscular ergot alkaloids vs no uterotonic agents

Pain after birth requiring analgesia (not prespecified) · women in the third stage of labour

Intravenous/intramuscular ergot alkaloids probably leads to higher pain after birth requiring analgesia (not prespecified) compared with no uterotonic agents (moderate certainty).

1 finding from 1 review