Number of participants reporting an adverse event · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
Intravenous diclofenac showed no clear difference in number of participants reporting any adverse event compared with another NSAID (low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
Intravenous diclofenac showed no clear difference in number of participants experiencing a serious adverse event compared with another NSAID (low certainty).
1 finding from 1 review
Median (mean) time to use of rescue medication · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
1 finding from 1 review
Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
Intravenous diclofenac may leads to lower number of participants using rescue medication over 4 to 6 hours… compared with placebo (low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
Intravenous diclofenac showed no clear difference in number of participants reporting any adverse event compared with placebo (low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
Intravenous diclofenac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).
1 finding from 1 review
At least 50% reduction in pain · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
2 findings from 1 review
Median (mean) time to use of rescue medication · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries
1 finding from 1 review
Endometritis · pregnant women undergoing caesarean section
Intravenous route showed no clear difference in endometritis compared with irrigation (lavage) (low certainty).
1 finding from 1 review
Wound infection · pregnant women undergoing caesarean section
It is very uncertain whether intravenous route changes wound infection compared with irrigation (lavage) (very low certainty).
1 finding from 1 review
Febrile morbidity · pregnant women undergoing caesarean section
It is very uncertain whether intravenous route changes postpartum febrile morbidity compared with irrigation (lavage) (very low certainty).
1 finding from 1 review
Urinary tract infection · pregnant women undergoing caesarean section
It is very uncertain whether intravenous route changes urinary tract infection compared with irrigation (lavage) (very low certainty).
1 finding from 1 review
Serious infectious complications · pregnant women undergoing caesarean section
1 finding from 1 review
Maternal adverse events · pregnant women undergoing caesarean section
1 finding from 1 review
Infant sepsis (suspected or proven) ‐ not measured · pregnant women undergoing caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Wound infection · colorectal surgery
Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).
2 findings from 1 review
Significant improvement in disability within 6 weeks · people with CIDP
Intravenous immunoglobulin leads to higher significant improvement in disability within 6 weeks compared with placebo (high certainty).
1 finding from 1 review
Change in mean disability score on Rankin scale · people with CIDP
1 finding from 1 review
Change in mean disability score at 24 weeks or later · people with CIDP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · people with CIDP
Intravenous immunoglobulin showed no clear difference in serious adverse events compared with prednisolone (moderate certainty).
1 finding from 1 review