Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

450 questions · 474 findings · 58 reviews

No studies found 96 · 20.3%GRADE not reported 49 · 10.3%Very low 102 · 21.5%Low 110 · 23.2%Moderate 77 · 16.2%High 40 · 8.4%

Intravenous/intramuscular ergot alkaloids vs no uterotonic agents

Pain after birth requiring analgesia (not prespecified) · women in the third stage of labour

Intravenous/intramuscular ergot alkaloids probably leads to higher pain after birth requiring analgesia (not prespecified) compared with no uterotonic agents (moderate certainty).

1 finding from 1 review

Intravenous/intramuscular ergot alkaloids vs no uterotonic agents

Maternal blood loss of 500 mL or greater · women in the third stage of labour

Intravenous/intramuscular ergot alkaloids may leads to lower estimated or measured blood loss of at least 500 mL visual estimation compared with no uterotonic agents (low certainty).

1 finding from 1 review

Summary of findings ‐ Intravenous lorazepam vs intranasal lorazepam

Seizure cessation: within 10 minutes · Children with acute tonic‐clonic seizures

Summary of findings ‐ Intravenous lorazepam showed no clear difference in seizure cessation: within 10 minutes compared with intranasal lorazepam (moderate certainty).

1 finding from 1 review