Cochrane · systematic review · CD011048
Prophylactic intravenous calcium therapy for exchange blood transfusion in the newborn
Ogunlesi, TA, Lesi, FEA, Oduwole, O · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 80%Low 1 · 20%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously versus EBT alone (change from baseline) for exchange blood transfusion in the newborn
Population: neonates receiving EBT
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause death Number of events Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously vs EBT alone (change from baseline) | no estimate extracted | 1 study · 30 participants | Low Downgraded: risk of bias |
Mean total serum calcium levels Mean difference Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously vs EBT alone (change from baseline) | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |
Mean ionised serum calcium levels Mean ionised serum calcium Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously vs EBT alone (change from baseline) | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |
Adverse reaction: cardiac arrest Number of events Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously vs EBT alone (change from baseline) | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |
Adverse reaction: apnoea and hypoglycaemia Number of events Pair‐wise comparison of exchange blood transfusion (EBT) plus 10% calcium gluconate intravenously vs EBT alone (change from baseline) | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |